GENERIC NAME: potassium
chloride
BRAND NAMES: K-Dur, K-Lor, K-Tab, Kaon CL,
Klorvess, Slow-K, Ten-K, Klotrix, K-Lyte CL
DRUG CLASS AND MECHANISM: Potassium chloride is in the
class of drugs called potassium supplements which are
used to treat low potassium conditions (hypokalemia)
or prevent them from occurring. Potassium is the principal
positive ion inside of the cells of the body and is
used in nerve conduction, muscle contraction, and normal
kidney function. A deficiency of potassium causes weakness,
fatigue, heart rhythm problems, paralysis, and kidney
dysfunction.
PRESCRIPTION: yes
GENERIC AVAILABLE: yes
PREPARATIONS: Tablets and capsules; 8 mEq,
10 mEq, 20mEq. Slow-K 8 mEq extended-release tablets;
Powder and liquid also available.
STORAGE: Potassium should be stored at room
temperature in a tight container.
PRESCRIBED FOR: Low potassium conditions
(hypokalemia) occur when the amount of potassium lost
in the kidneys or intestines exceeds the amount of potassium
taken in. This usually occurs slowly with the use of
diuretics. However, it can also occur in diabetic ketoacidosis,
severe diarrhea, conditions wherein the patient is receiving
IV fluids and not eating, and rare disorders of the
adrenal glands. Potassium chloride is used to treat
hypokalemia and to prevent hypokalemia from occurring
when strong diuretics are used. Potassium can also be
used to treat digitalis toxicity.
DOSING: Potassium is usually taken with
meals and fluids to prevent intestinal problems.
DRUG INTERACTIONS: Cardiac arrest can occur
with high potassium conditions, such as chronic renal
failure, burns, acidosis, dehydration, and potassium
sparing diuretic usage. Potassium supplements should
not be given to these patients. Ulcers and bleeding
can occur in patients with intestinal problems, especially
those who are taking slow- release tablets. Drug interactions
causing elevation of potassium can occur with ACE inhibitors
(used to treat high blood pressure) and certain diuretics
(aldactone and triamterene). Blood tests to measure
potassium levels should be followed regularly in these
patients. Slow-release tablets should be swallowed,
not chewed or crushed.
SIDE EFFECTS: Severe side effects include
high potassium and intestinal bleeding, ulceration,
and perforation as mentioned above in
DRUG INTERACTIONS. More common reactions
include nausea, vomiting, diarrhea, and abdominal pain.
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